High placental expression of FLT1, LEP, PHYHIP and IL3RA - In persons of African ancestry with severe preeclampsia.
Omonigho AisagbonhiTony BuiChanond A NasamranHailee St LouisDonald PizzoMorgan MeadsMegan MulhollandCelestine MagallanesLeah Lamale-SmithLouise C LaurentRobert MoreyMarni B JacobsKathleen M FischMariko HoriiPublished in: Placenta (2023)
High placental upregulation of both canonical preeclampsia and allograft rejection/adaptive immune response genes may contribute to worse PE outcomes in African ancestry sPE patients.
Keyphrases
- early onset
- immune response
- poor prognosis
- end stage renal disease
- ejection fraction
- newly diagnosed
- acute myeloid leukemia
- rheumatoid arthritis
- prognostic factors
- genome wide
- tyrosine kinase
- signaling pathway
- type diabetes
- pregnant women
- binding protein
- toll like receptor
- long non coding rna
- adipose tissue
- high resolution
- transcription factor
- kidney transplantation
- systemic lupus erythematosus
- bioinformatics analysis
- drug induced