Community-acquired pneumonia subgroups and differential response to corticosteroids: a secondary analysis of controlled studies.
Esther WittermansPhilip A van der ZeeHongchao QiEwoudt M W van de GardeClaudine A BlumMirjam Christ-CrainDiederik GommersJan C GruttersG Paul VoornWillem Jan W BosHenrik EndemanPublished in: ERJ open research (2022)
In two independent cohorts, LCA identified two classes of CAP patients with different clinical characteristics and outcomes. Given the different response to adjunctive corticosteroids in the Ovidius trial, LCA might provide a useful basis to improve patient selection for future trials.