Does tranexamic acid lead to changes in MRI measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? Protocol for a MRI substudy nested within the double-blind randomised controlled TICH-2 trial.
Rob A DineenStefan PszczolkowskiKatie FlahertyZhe K LawPaul S MorganIan RobertsDavid J WerringRustam Al-Shahi SalmanTim EnglandPhilip M BathNikola SpriggPublished in: BMJ open (2018)
ISRCTN93732214; Pre-results.
Keyphrases
- study protocol
- contrast enhanced
- magnetic resonance imaging
- clinical trial
- phase iii
- double blind
- randomized controlled trial
- diffusion weighted imaging
- phase ii
- healthcare
- placebo controlled
- white matter
- computed tomography
- health information
- open label
- resting state
- cerebral ischemia
- risk assessment
- social media
- blood brain barrier
- health promotion
- brain injury
- subarachnoid hemorrhage