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Potential added value of a RT-qPCR method of SOX 11 expression, in the context of a multidisciplinary diagnostic assessment of B cell malignancies.

Julien MagneAlizée JenvrinAdrien ChauchetOlivier CasasnovasAnne DonzelLaurence JegoBernard AralJulien GuyNathalie NadalDewi VernereyPatrick CallierFrancine Garnache-OttouChristophe Ferrand
Published in: Experimental hematology & oncology (2018)
This work describes an RT-qPCR assay for SOX11 expression in order to better characterize MCL at diagnosis. Further studies on larger cohorts are needed to evaluate this molecular tool, especially for the follow-up of minimal residual disease.
Keyphrases
  • poor prognosis
  • transcription factor
  • stem cells
  • human health