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Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation.

Li ChenKaikai ShiWeimin QiuLars AagaardMoustapha Kassem
Published in: Stem cells international (2020)
hMSC-CRISPRi and hMSC-CRISPRa are useful resources to study genes and genetic pathways regulating lineage-specific differentiation of hMSC.
Keyphrases
  • genome wide
  • endothelial cells
  • copy number
  • genome wide identification
  • transcription factor
  • bone marrow
  • induced pluripotent stem cells
  • pluripotent stem cells