A systematic review and network meta-analysis of current and investigational treatments for active ankylosing spondylitis.

Atul A DeodharS D ChakravartyC CameronS PetersonR HensmanS FogartyP SpinS KafkaS NairL S Gensler

Published in: Clinical rheumatology (2020)

Two approved therapies (golimumab IV, infliximab) and one investigational product ranked highest for efficacy in AS. Key Points • Although golimumab IV, infliximab, and tofacitinib ranked highest for efficacy in AS, differences in efficacy between approved and investigational therapies were not statistically significant.

Keyphrases

ankylosing spondylitis
ulcerative colitis
rheumatoid arthritis
disease activity
phase ii
randomized controlled trial