The non-specific nature of mental health and structural brain outcomes following childhood trauma.
Theresa K HaidlDennis M HedderichMarlene RosenNathalie KaiserMauro SevesThorsten LichtensteinNora PenzelJulian WenzelLana Kambeitz-IlankovicAnne RuefDavid PopovicFrauke Schultze-LutterKatharine ChisholmRachel UpthegroveRaimo K R SalokangasChristos PantelisEva MeisenzahlStephen J WoodPaolo BrambillaStefan BorgwardtStephan RuhrmannJoseph KambeitzNikolaos KoutsoulerisPublished in: Psychological medicine (2021)
These results indicate that CT poses a transdiagnostic risk factor for mental health disorders, possibly related to depressive symptoms. While differences in the quality of CT exposure exist, diagnostic differentiation was not possible suggesting a multi-factorial pathogenesis.