Role of High-Dose Chemotherapy and Autologous Hematopoietic Cell Transplantation for Children and Young Adults with Relapsed Ewing's Sarcoma: A Systematic Review.
Pavan TennetiUmar ZahidAhmad IftikharSeongseok YunAtif SohailZabih WarraichFaiz AnwarPublished in: Sarcoma (2018)
Most studies using HDCT/ASCT as consolidation regimen showed improved survival benefits compared to CC. Randomized controlled studies are needed to determine true clinical benefits of HDCT followed by ASCT in patients with RES.
Keyphrases
- young adults
- high dose
- case control
- low dose
- double blind
- acute lymphoblastic leukemia
- acute myeloid leukemia
- open label
- bone marrow
- diffuse large b cell lymphoma
- placebo controlled
- phase iii
- multiple myeloma
- phase ii
- cell therapy
- hodgkin lymphoma
- randomized controlled trial
- childhood cancer
- clinical trial
- squamous cell carcinoma
- free survival
- radiation therapy
- platelet rich plasma
- mesenchymal stem cells