Case report: Unilateral optic nerve aplasia and developmental hemi-chiasmal dysplasia with VEP misrouting.
Siân E HandleyOliver Rajesh MarmoySri K GoreKshitij MankadDorothy Ann ThompsonPublished in: Documenta ophthalmologica. Advances in ophthalmology (2020)
This infant has chiasmal misrouting in association with unilateral optic nerve aplasia and unilateral microphthalmos. Chiasmal misrouting has not been found in patients with microphthalmos or anophthalmos, but has been reported after early eye loss in animal models. Our findings contribute to our understanding of the discrepancy between the visual pathway physiology of human unilateral microphthalmia and animal models.