Protopanaxadiol prevents cisplatin-induced acute kidney injury by regulating ferroptosis.

Zeyu SongZhenyuan LiTao PanTeng LiuBaifang GongZhixia WangKe LiuHua-Ying Fan

Published in: The Journal of pharmacy and pharmacology (2024)

PPD has an inhibitory effect on cisplatin-induced nephrotoxicity, which may be related to the inhibition of ferroptosis by regulating iron metabolism and lipid peroxidation.

Keyphrases

acute kidney injury
cell death
cardiac surgery
drug induced
fatty acid
mouse model