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Aberrant expression of HMB45 and negative PRAME expression in halo nevi.

Kristen N RubyZhongze LiShaofeng Yan
Published in: Journal of cutaneous pathology (2020)
Aberrant HMB45 expression in NHP is not uncommon and may be a diagnostic pitfall. Negative PRAME immunostaining may be a reassuring finding to help differentiate halo nevus from malignant melanoma.
Keyphrases
  • poor prognosis
  • binding protein