Specificity of affective dynamics of bipolar and major depressive disorder.
Emma K StappVadim ZipunnikovAndrew LerouxLihong CuiMathilde M HuskyDebangan DeyKathleen R MerikangasPublished in: Brain and behavior (2023)
Bipolar-I is more strongly characterized by activation and energy than sad and anxious mood. This distinction has potential implications for both specificity of intervention targets and differential pathways underlying these dynamic affective systems. Confirmation of the longer term stability and generalizability of these findings in future studies is necessary.