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Immune surveillance for vaccine-preventable diseases.

Gerco den HartogRobert S van BinnendijkAnne-Marie BuismanGuy A M BerbersFiona R M van der Klis
Published in: Expert review of vaccines (2020)
In order to perform multicenter studies on many samples for multiple antigens, more validated reference materials and wider adoption of high-throughput techniques are needed. The field of serosurveillance will also benefit from better correlates of protection and understanding of (local) mechanisms of protection. Here we give an overview of the current state-of-the-art of serosurveillance and how the field could move forward.
Keyphrases
  • high throughput
  • single cell
  • cross sectional
  • emergency department
  • clinical trial
  • case control
  • immune response