Conserved phylogenetic distribution and limited antibiotic resistance of class 1 integrons revealed by assessing the bacterial genome and plasmid collection.
An Ni ZhangLi-Guan LiLiping MaMichael R GillingsJames M TiedjeTong ZhangPublished in: Microbiome (2018)
The above observations indicated that there are both biological and ecological limitations to class 1 integrons in acquiring and spreading ARGs across different classes of the domain Bacteria.