Effects of Low-Energy Diet or Exercise on Cardiovascular Function in Working-Age Adults With Type 2 Diabetes: A Prospective, Randomized, Open-Label, Blinded End Point Trial.
Gaurav Singh GulsinDaniel J SwarbrickLavanya AthithanEmer M BradyJoseph HensonEmma BaldryStavroula ArgyridouNishal B JaicimGareth SquireYvette WaltersAnna-Marie MarshJohn McAdamKelly S ParkeJohn D BiglandsThomas YatesKamlesh Khunti F MedSciMelanie J DaviesGerry P McCannPublished in: Diabetes care (2020)
In asymptomatic working-age adults with T2D, exercise training improved diastolic function. Despite beneficial effects of weight loss on glycemic control, concentric LV remodeling, and aortic stiffness, a low-energy MRP did not improve diastolic function.
Keyphrases
- weight loss
- glycemic control
- left ventricular
- open label
- study protocol
- type diabetes
- blood pressure
- bariatric surgery
- clinical trial
- physical activity
- phase ii
- heart failure
- blood glucose
- high intensity
- roux en y gastric bypass
- aortic valve
- randomized controlled trial
- ejection fraction
- squamous cell carcinoma
- adipose tissue
- gastric bypass
- insulin resistance
- phase ii study
- pulmonary arterial hypertension
- rectal cancer