Electroencephalography-based investigation of the effects of oral desmopressin on improving slow-wave sleep time in nocturnal polyuria patients (the DISTINCT study): A single-arm, open-label, single-assignment trial.
Kazumasa TorimotoDaisuke GotohYasushi NakaiMakito MiyakeKiyohide FujimotoPublished in: Neurourology and urodynamics (2024)
Oral administration of 50 μg desmopressin improved nocturnal frequency and FUSP in older individuals with NP but did not significantly enhance sleep quality. In older adults, decreased nighttime urinary frequency may enhance quality of life; however, its influence on objective sleep quality may be limited.
Keyphrases
- sleep quality
- physical activity
- depressive symptoms
- open label
- end stage renal disease
- clinical trial
- newly diagnosed
- ejection fraction
- phase iii
- study protocol
- phase ii
- chronic kidney disease
- prognostic factors
- randomized controlled trial
- radiation therapy
- obstructive sleep apnea
- patient reported outcomes
- community dwelling