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Is there any correlation among MKK4 (mitogen-activated protein kinase kinase 4) expression, clinicopathological features, and KRAS/NRAS mutation in colorectal cancer.

Mutlu DoganServet GuresciYusuf AcikgozYakup ErgünFahriye Tugba KosOnder BozdoganÖznur Bal
Published in: Expert review of molecular diagnostics (2020)
MKK4 expression inversely correlates with survival outcomes. Patients with KRAS/NRAS wild-type, left-sided tumors with WIR had longer OS.
Keyphrases
  • wild type
  • poor prognosis
  • protein kinase
  • tyrosine kinase
  • binding protein