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COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Miklos GulyasJohanna Sofia Margareta MattssonAndrea LindgrenLars EkKristina Lamberg LundströmAnnelie BehndigErik Carl Viktor HolmbergPatrick MickeBengt Bergmannull null
Published in: Acta oncologica (Stockholm, Sweden) (2017)
In this subgroup analysis of patients with advanced NSCLC treated within the context of a randomized trial, we could not detect any interaction effect of COX-2 expression in tumor or stromal cells and the outcome of celecoxib treatment in addition to standard chemotherapy.
Keyphrases
  • advanced non small cell lung cancer
  • poor prognosis
  • epidermal growth factor receptor
  • locally advanced
  • small cell lung cancer
  • binding protein
  • long non coding rna
  • open label