m.4216 T > C polymorphism in JT cluster determines a lower pregnancy rate in response to controlled ovarian stimulation treatment.
Belén Monge-OchoaLuis MontoroJulio MontoyaEduardo Ruiz-PesiniManuel J López-PérezFrancisco de CastroCarmen Díez-SánchezPublished in: Journal of assisted reproduction and genetics (2023)
JT cluster shows a different influence of TD FSH on RO. JT cluster shows higher RO and E than U, but it is Uk which exhibits a significant higher pregnancy rate than JT. The negative influence of the JT cluster on pregnancy success strongly suggests that the m.4216 T > C polymorphism could be responsible.