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The gRAMP CRISPR-Cas effector is an RNA endonuclease complexed with a caspase-like peptidase.

Sam P B van BeljouwAnna C HaagsmaAlicia Rodríguez-MolinaDaan F van den BergJochem N A VinkStan J J Brouns
Published in: Science (New York, N.Y.) (2021)
[Figure: see text].
Keyphrases
  • crispr cas
  • genome editing
  • cell death
  • dna repair
  • regulatory t cells
  • induced apoptosis
  • dendritic cells
  • smoking cessation
  • type iii
  • nucleic acid
  • endoplasmic reticulum stress
  • immune response