Vaccination with designed neopeptides induces intratumoral, cross-reactive CD4+ T cell responses in glioblastoma.
Jian WangTobias WeissMarian Christoph NeidertNora C ToussaintReza NaghavianCarla Moreno SellésMagdalena FoegePaula Tomas OjerGioele MediciIvan JelcicDaniel SchulzElisabeth J RushingSusanne DettwilerBarbara SchrörsJoo-Heon ShinRon McKayCatherine J WuAndreas LutterottiMireia SospedraHolger MochErich F GreinerBernd BodenmillerLuca RegliMichael WellerPatrick RothRoland MartinPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Turning tumor self-peptides into foreign antigens by introduction of designed mutations is a promising strategy to induce strong intratumoral CD4+ T cell responses in a cold tumor like glioblastoma.
Keyphrases