A bacterial route for folic acid supplementation.
Claire MaynardIan CumminsJacalyn GreenDavid WeinkovePublished in: BMC biology (2018)
Folic acid supplementation in C. elegans occurs chiefly indirectly via bacterial uptake of breakdown products via E. coli AbgT, and can impact C. elegans development and longevity. Examining how folic acid supplementation affects bacterial folate synthesis in the human gut may help us to better understand the safety of folic acid supplementation.