Piperacillin/tazobactam for surgical prophylaxis during pancreatoduodenectomy: meta-analysis.

Jayant Kumar Isabella RecciaAdriano CarneiroMauro PoddaFrancesco VirdisNikolaos MachairasDavid NasrallaRamesh P ArasaradnamKenneth PoonChristopher J GannonJohn J Fung Nagy A HabibOmar Llaguna

Published in: BJS open (2024)

Piperacillin/tazobactam as antimicrobial prophylaxis significantly lowers the risk of postoperative surgical-site infections, major surgical complications (complications classified as Clavien-Dindo grade greater than or equal to III), clinically relevant postoperative pancreatic fistulas (grades B and C), and mortality, hence supporting the implementation of piperacillin/tazobactam for surgical prophylaxis in current practice.

Keyphrases

systematic review
primary care
risk factors
patients undergoing
healthcare
gram negative
staphylococcus aureus
quality improvement
cardiovascular events
randomized controlled trial
type diabetes
meta analyses
coronary artery disease
case control