Enabling Combinatorial siRNA Delivery against Apoptosis-Related Proteins with Linoleic Acid and α-Linoleic Acid Substituted Low Molecular Weight Polyethylenimines.

Samarwadee PlianwongBindu ThapaRemant Bahadur KcCezary KucharskiTheerasak RojanarataHasan Uludağ

Published in: Pharmaceutical research (2020)

This study yielded effective siRNA carriers for combinational delivery of siRNAs. Careful choice of siRNA combinations will be critical since targeting individual genes might alter the expression of other critical mediators.

Keyphrases

cancer therapy
drug delivery
poor prognosis
hyaluronic acid
oxidative stress
endoplasmic reticulum stress
cell death
cell cycle arrest
binding protein
long non coding rna
signaling pathway
transcription factor
genome wide identification