Robust Immune Response Induced by Schistosoma mansoni TSP-2 Antigen Coupled to Bacterial Outer Membrane Vesicles.

Mayra M Ferrari BarbosaAlex I KannoGiovana Cappio BarazzoneDunia RodriguezVioleta PancakovaMonalisa TrentiniEliana L Faquim-MauroAmanda P FreitasMariana I KhouriJessica Lobo-SilvaViviane M GoncalvesRocilda P F SchenkmanMartha M TanizakiDiana BoraschiRichard MalleyLeonardo P FariasLuciana C C Leite

Published in: International journal of nanomedicine (2021)

Our results demonstrate that the SmTSP-2 antigen coupled with OMVs is highly immunogenic in mice, supporting the potential effectiveness of this platform for improved antigen delivery in novel vaccine strategies.

Keyphrases

immune response
randomized controlled trial
systematic review
high throughput
type diabetes
dendritic cells
metabolic syndrome
adipose tissue
climate change