Association study between single-nucleotide variants rs12097821, rs2477686, and rs10842262 and idiopathic male infertility risk in Serbian population with meta-analysis.

Vucic NemanjaDobrijevic ZoranaKotarac NevenaMatijasevic SuzanaVukovic IvanBudimirovic BrankoDjordjevic MirkaSavic-Pavicevic DusankaBrajuskovic Goran

Published in: Journal of assisted reproduction and genetics (2020)

Our results show variants rs2477686 and rs10842262 to be significantly associated with male infertility in the Serbian population. Nevertheless, case-control studies in other populations are needed to validate their association with infertility in males diagnosed with oligoasthenozoospermia and non-obstructive azoospermia.

Keyphrases

case control
systematic review
copy number
polycystic ovary syndrome
dna methylation
gene expression
randomized controlled trial
meta analyses