Evaluation of Pembrolizumab Monotherapy Efficacy in Advanced Non-Small-Cell Lung Cancer by Serial Monitoring of Circulating Tumor DNA Using Next-Generation Sequencing.

Buhai WangYaqin FanLiying ZhangLiqin LiuYutong MaXiaosong MaYuxiang HuangYinxia WuYichen LiangYang XuXue Wu

Published in: Clinical Medicine Insights. Oncology (2022)

Genomic profiling of peripheral blood samples can be applied to dynamically monitor disease progression. The reduction in ctDNA concentration during treatment implied DCBs.

Keyphrases

circulating tumor
advanced non small cell lung cancer
peripheral blood
epidermal growth factor receptor
cell free
circulating tumor cells
combination therapy
copy number
single cell
open label
tyrosine kinase
randomized controlled trial
clinical trial
genome wide