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Effect of Pharmacotherapy for Overactive Bladder on the Incidence of and Factors Related to Urinary Tract Infection: A Systematic Review and Meta-analysis.

Kazuna TsubouchiHisatomi ArimaMakiko AbeHiroshi MatsuzakiKosuke TominagaAiko FujikawaNaotaka GungeTakeshi MiyazakiYu OkabeNobuyuki NakamuraHirofumi MatsuokaShota OkutsuKazuhiro TadaNobuhiro Haga
Published in: The Journal of urology (2023)
This meta-analysis showed that antimuscarinic agents statistically significantly increased the incidences of urinary tract infection and lower urinary tract symptoms and dysfunction, but beta 3-adrenoceptor agonists did not. To prevent urinary tract infection emergence, beta 3-adrenoceptor agonists might be safer than antimuscarinic agents.
Keyphrases
  • urinary tract infection
  • lower urinary tract symptoms
  • systematic review
  • benign prostatic hyperplasia
  • oxidative stress
  • randomized controlled trial