Metabolic engineering of Caldicellulosiruptor bescii for 2,3-butanediol production from unpretreated lignocellulosic biomass and metabolic strategies for improving yields and titers.
Tania N N TanweeGina L LipscombJason L VailionisKe ZhangRyan G BingHailey C O'QuinnFarris L PooleYing ZhangRobert M KellyMichael W W AdamsPublished in: Applied and environmental microbiology (2023)
was applied to adjust carbon and redox fluxes to maximize productivity of 2,3-butanediol, thereby revealing bottlenecks that require genetic modifications.