Voluntary suspension of medically-assisted reproduction during the COVID-19 pandemic in Japan: a nationwide internet survey.

We explored whether coronavirus disease 2019 (COVID-19)-related distress was associated with voluntary suspension of medically-assisted reproduction (MAR) treatment from April to May 2020 in Japan. Data for 1,096 candidate respondents were collected from a Japanese nationwide cross-sectional internet survey distributed from August 25 to September 30, 2020. Multiple logistic regression was performed to clarify the association between voluntary suspension of MAR treatment and the Fear of COVID-19 Scale (FVC-19S) score. High FCV-19S score was inversely associated with voluntary suspension of MAR treatment compared to low FCV-19S score among women (OR = 0.28, 95% CI = 0.10-0.84). Age-stratified analyses revealed that low FVC-19S score was significantly associated with voluntary suspension of MAR treatment among women aged < 35 years (OR = 3.86, 95% CI = 1.35-11.0). In contrast, the association between FVC-19S score and voluntary suspension of MAR treatment was reversed and not significant among women aged ≥ 35 years (OR = 0.67, 95% CI = 0.24-1.84). COVID-19-related distress was significantly associated with voluntary suspension of MAR treatment among women aged < 35 years, and this association was reversed but not significant among women aged ≥ 35 years.