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Vector design for enhancing expression level and assembly of knob-into-hole based FabscFv-Fc bispecific antibodies in CHO cells.

Han Kee OngNgan T B NguyenJiawu BiSteven C L Ho
Published in: Antibody therapeutics (2022)
The results obtained in this work provide insights to the impacts of hetero-chain ratios on the BsAb production.
Keyphrases
  • induced apoptosis
  • poor prognosis
  • cell cycle arrest
  • oxidative stress
  • binding protein
  • long non coding rna
  • cell proliferation