Quantifying the net expression of metabolites allows for the identification of cells with metabolic pathways that result in increased biomolecule production, which is essential for improving the yield and reducing the cost of industrial biomanufacturing. Technological advancements in vibrational microscopy instrumentation will greatly benefit biofoundries as a complementary approach for non-destructive cell screening.
Keyphrases
- single cell
- high resolution
- ms ms
- cell therapy
- induced apoptosis
- density functional theory
- molecular dynamics simulations
- poor prognosis
- escherichia coli
- heavy metals
- wastewater treatment
- high throughput
- microbial community
- energy transfer
- mesenchymal stem cells
- signaling pathway
- mass spectrometry
- quantum dots
- raman spectroscopy