Mechanical stress stimulates the osteo/odontoblastic differentiation of human stem cells from apical papilla via erk 1/2 and JNK MAPK pathways.

Chao MuTaohong LvZilu WangShu MaJie MaJin LiuJinhua YuJinquan Mu

Published in: BioMed research international (2014)

Together, these findings suggest that mechanical stress is an important factor affecting the proliferation and differentiation of SCAPs via the activation of ERK and JNK signaling pathway.

Keyphrases

signaling pathway
pi k akt
induced apoptosis
epithelial mesenchymal transition
endothelial cells
stress induced
induced pluripotent stem cells
pluripotent stem cells