Increasing prevalence of a fluoroquinolone resistance mutation amongst Campylobacter jejuni isolates from four human infectious intestinal disease studies in the United Kingdom.
Sam HaldenbyChristina BronowskiCharlotte NelsonJohn KennyCarmen Martinez-RodriguezRoy ChaudhuriNicola J WilliamsKen ForbesNorval J StrachanJane PulmanIan N WinstanleyCaroline E CorlessTom J HumphreyFrederick J BoltonSarah J O'BrienNeil HallChristiane Hertz-FowlerCraig WinstanleyPublished in: PloS one (2020)
Four population-based studies of community diarrhoea over a 25 year period revealed an increase over time in the prevalence of the T86I amongst isolates of C. jejuni associated with human gastrointestinal disease in the UK. Although associated with many STs, much of the increase is due to the expansion of clones associated with the resistance mutation.