Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population.

Pattarin TangtanatakulChisanu ThumaratNusara SatproedpraiPunna KunhapanTassamonwan ChaiyasungSiriwan KlinchanhomYong-Fei WangWei WeiJeerapat WongshinsriDirekrit ChiewchengcholPongsawat RodsawardPintip NgamjanyapornThanitta SuangtamaiSurakameth MahasirimongkolPrapaporn PisitkunNattiya Hirankarn

Published in: Arthritis research & therapy (2020)

We demonstrated the genetic architecture of SLE in the Thai population and identified a novel locus associated with SLE. Also, our study suggested a potential use of the PRS model from the Chinese population to estimate the disease risk for individuals of Thai ancestry.

Keyphrases

genome wide association study
systemic lupus erythematosus
disease activity
systematic review
genome wide
rheumatoid arthritis
gene expression
randomized controlled trial
risk assessment
human health
climate change