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Seroprevalence of sporotrichosis infection in cats living in the Buenos Aires epizootic area.

Alejandro N EtchecopazCarolina Rodríguez LaboccettaGustavo MartinezFlorencia PastorinoLeandro DíazAna C BratanichPaula BadinoJavier MasAdriana I ToranzoCristina E CanterosMaría Luján Cuestas
Published in: Medical mycology (2023)
This study aimed to perform a seroepidemiological survey on the prevalence of sporotrichosis among cats living in the Northern area of Buenos Aires, where a four-fold increase of Sporothrix brasiliensis infections were diagnosed during the last decade. For this purpose, an in-house indirect ELISA test sensitized with S. brasiliensis crude antigens was used. The ELISA test showed 100.0% sensitivity and 95.0% specificity. Antibodies against S. brasiliensis antigens were detected in 3.7% (9/241) of healthy cats evaluated, suggesting likely exposure or infection to this fungus. This ELISA test would be a valuable screening tool for diagnosing sporotrichosis and for seroepidemiological surveys.
Keyphrases
  • cross sectional
  • dendritic cells
  • monoclonal antibody
  • risk factors
  • immune response
  • structural basis
  • disease virus