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Validation and interpretation of Pan-TRK immunohistochemistry: a practical approach and challenges with interpretation.

Cansu KarakasEllen J GiampoliTanzy LoveDavid G HicksMoises J Velez
Published in: Diagnostic pathology (2024)
Pan-TRK IHC shows some utility as a diagnostic and surrogate marker for NTRK screening however, physiologic or non-specific expression may lead to false-positive results.
Keyphrases
  • poor prognosis
  • binding protein