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Epigenetic regulation of human-specific gene expression in the prefrontal cortex.

Weifen SunGangcai XieXi JiangPhilipp KhaitovichDingding HanXiling Liu
Published in: BMC biology (2023)
Our results comprehensively elucidated a causal species-specific gene-histone-enzyme landscape in the prefrontal cortex and highlighted the regulatory interaction that drove transcriptional activation.
Keyphrases
  • prefrontal cortex
  • gene expression
  • dna methylation
  • transcription factor
  • endothelial cells
  • genome wide
  • induced pluripotent stem cells
  • copy number
  • pluripotent stem cells
  • oxidative stress
  • heat stress