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A Multi-Step Model of Parkinson's Disease Pathogenesis.

Campbell J Le HeronMichael R MacAskillDeborah MasonJohn Dalrymple-AlfordTim AndersonToni L PitcherDaniel J Myall
Published in: Movement disorders : official journal of the Movement Disorder Society (2021)
The age-specific incidence of PD is consistent with a process that develops in multiple, discrete steps - on average six before age 45 and eight after. The model supports theories emphasizing the primacy of environmental factors in driving sex differences in PD incidence. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
  • risk factors
  • randomized controlled trial