Comparison between Heat-Clearing Medicine and Antirheumatic Medicine in Treatment of Gastric Cancer Based on Network Pharmacology, Molecular Docking, and Tumor Immune Infiltration Analysis.

Jiamin XuFuqin KangWei WangShujun LiuJianhui Xie Xiaobo Yang

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

Quercetin is an important ingredient in both heat-clearing medicine and antirheumatic medicine. AR signaling pathway exists in both types of medicines. The mechanism of the antitumor effect in antirheumatic medicine was similar to trastuzumab, a targeted drug aimed at ERBB2. Both types of medicines were significant in tumor immune infiltration. The immunology of gastric tumor deserves further research.

Keyphrases

molecular docking
rheumatoid arthritis
signaling pathway
rheumatoid arthritis patients
molecular dynamics simulations
drug delivery
epithelial mesenchymal transition
epidermal growth factor receptor
pi k akt
combination therapy