Decidual leucocytes infiltrating human spiral arterioles are rich source of matrix metalloproteinases and degrade extracellular matrix in vitro and in situ.
Ruhul H ChoudhuryCaroline E DunkStephen J LyeLynda K HarrisJohn D AplinRebecca L JonesPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2018)
We suggest that matrix remodelling in SpA is initiated by infiltrating leucocytes, while EVTs become involved at later stages.