Metabolic Syndrome Predisposes to Osteoarthritis: Lessons from Model System.

Samuel Joshua Pragasam Sampath Vijayalakshmi Venkatesan

Published in: Cartilage (2020)

Multiple metabolic perturbations featured in WNIN/Gr-Ob rats were effective to induce spontaneous OA-like degenerative changes affecting knee joints akin to human OA.

Keyphrases

knee osteoarthritis
metabolic syndrome
endothelial cells
total knee arthroplasty
induced pluripotent stem cells
rheumatoid arthritis
insulin resistance
pluripotent stem cells
uric acid
type diabetes
cardiovascular disease
cardiovascular risk factors
skeletal muscle