Population Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics Modeling of Oxypurinol in Hmong Adults with Gout and/or Hyperuricemia.
Ya-Feng WenRichard C BrundageYoussef M RomanKathleen A Culhane-PeraRobert J StrakaPublished in: British journal of clinical pharmacology (2023)
The proposed allopurinol dosing guide uses individuals' fat-free mass, renal function, and SLC22A12 rs505802 and PDZK1 rs12129861 genotypes to achieve target SU.