Imaging Epigenetics of Prenatal THC.
Nicole R ZürcherVictoria H J RobertsMatthias C SchabelAndrea G EdlowJacob M HookerJamie O LoPublished in: ACS chemical neuroscience (2021)
Prenatal exposure to marijuana may lead to epigenetic alterations in the placenta and fetal brain, affecting short- and long-term offspring health. This Viewpoint addresses the critical need to study and characterize the impact of maternal marijuana use and consequences of in utero exposure on later development and health. We highlight the development of new PET imaging tools and the opportunity for longitudinal in vivo non-human primate studies to help elucidate epigenetic changes resulting from prenatal marijuana exposure throughout gestation.
Keyphrases
- pet imaging
- pregnant women
- public health
- healthcare
- dna methylation
- gene expression
- mental health
- endothelial cells
- health information
- high resolution
- preterm infants
- resting state
- health promotion
- type diabetes
- computed tomography
- induced pluripotent stem cells
- body mass index
- birth weight
- pluripotent stem cells
- risk assessment
- climate change
- brain injury
- physical activity