Association of decreased triadin expression level with apoptosis of dopaminergic cells in Parkinson's disease mouse model.

Min Hyung SeoSabina LimSujung Yeo

Published in: BMC neuroscience (2021)

Decreased TRDN level could be related with the apoptotic death of dopaminergic cells at the SN in PD, and TRDN administration could give a positive effect on PD by reducing apoptotic cell death.

Keyphrases

cell death
cell cycle arrest
induced apoptosis
mouse model
endoplasmic reticulum stress
pi k akt
oxidative stress
poor prognosis
signaling pathway
drug induced