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Effects of miR-672 on the angiogenesis of adipose-derived mesenchymal stem cells during bone regeneration.

Mingjiao ChenMeng ZhouYao FuJin LiZi Wang
Published in: Stem cell research & therapy (2021)
BMP2 could promote the angiogenesis of ADSCs through stimulating the expression of miR-672 in ADSCs. miR-672 acted as a positive regulator on the angiogenesis of ADSCs, and incorporating the miR-672-modified ADSCs in the CPC could significantly promote the vascularization and the bone regeneration.
Keyphrases
  • bone regeneration
  • cell proliferation
  • long non coding rna
  • mesenchymal stem cells
  • long noncoding rna
  • endothelial cells
  • poor prognosis
  • vascular endothelial growth factor
  • wound healing
  • stem cells
  • cell therapy