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Effectiveness of booster dose of tetanus and diphtheria toxoids (Td) vaccine in management of recurrent aphthous stomatitis: a prospective, randomized, triple-blind and placebo-controlled clinical trial.

Shahram HabibzadehMehdi Sheikh RahimiHasan EdalatkhahHadi PiriNasrollah Maleki
Published in: The Journal of dermatological treatment (2019)
A booster dose of Td vaccine had relatively favorable effects on pain intensity and recurrence of RAS, but further research is needed to confirm its efficacy.
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