ITGA5 Promotes Tumor Progression through the Activation of the FAK/AKT Signaling Pathway in Human Gastric Cancer.

Jun-Fu Wang Ye-Yang ChenSi-Wen ZhangKun ZhaoYue QiuYe WangJian-Cheng WangZhu YuBo-Pei LiZheng WangJun-Qiang Chen

Published in: Oxidative medicine and cellular longevity (2022)

ITGA5 promotes proliferation, invasion, and migration of gastric cancer cells through the activation of FAK/AKT signaling pathway, suggesting that ITGA5 may be potentially considered as a new target in gastric cancer therapy.

Keyphrases

signaling pathway
cell migration
cancer therapy
pi k akt
induced apoptosis
epithelial mesenchymal transition
endothelial cells
drug delivery
induced pluripotent stem cells
pluripotent stem cells
oxidative stress