Objective analysis and clinical significance of the spatial tumor infiltrating lymphocyte patterns in non-small cell lung cancer (NSCLC).
Miguel Lopez de RodasYvonne WangGang PengJian-Lei GuMari A Mino-KenudsonJonathan W RiessVamsidhar VelchetiMatthew D HellmannJustin F GainorHongyu ZhaoKurt A SchalperPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Our results identified major challenges associated with the qualitative spatial TIL pattern evaluation. We devised a novel objective strategy to overcome some of these limitations that has strong biomarker potential.