Matthew D Hellmann (Matthew Hellmann)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 55

Top Topics

Squamous Cell Carcinoma

Clinical Practice

Epidermal Growth Factor Receptor

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Cancer immunology research

Cancer discovery

Journal for immunotherapy of cancer

This page only lists publications with an associated author ORCID identifier.

Publications

Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-Related Colitis Is Associated with Fecal Microbial Dysbiosis and Can Be Mitigated by Fecal Microbiota Transplantation. Cancer immunology research 12 (3) (2024)
Miguel Lopez de Rodas, Yvonne Wang, Gang Peng, Jian-Lei Gu, Mari A Mino-Kenudson, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin F Gainor, Hongyu Zhao, Kurt A Schalper
Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (5) (2024)
Miguel Lopez de Rodas, Yvonne Wang, Gang Peng, Jian-Lei Gu, Mari A Mino-Kenudson, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin F Gainor, Hongyu Zhao, Kurt A Schalper
Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (5) (2024)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-Related Colitis Is Associated with Fecal Microbial Dysbiosis and Can Be Mitigated by Fecal Microbiota Transplantation. Cancer immunology research 12 (3) (2024)
Miguel Lopez de Rodas, Yvonne Wang, Gang Peng, Jian-Lei Gu, Mari A Mino-Kenudson, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin F Gainor, Hongyu Zhao, Kurt A Schalper
Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (5) (2024)
Miguel Lopez de Rodas, Yvonne Wang, Gang Peng, Jian-Lei Gu, Mari A Mino-Kenudson, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin F Gainor, Hongyu Zhao, Kurt A Schalper
Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (5) (2024)
Miguel Lopez de Rodas, Yvonne Wang, Gang Peng, Jian-Lei Gu, Mari A Mino-Kenudson, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin F Gainor, Hongyu Zhao, Kurt A Schalper
Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (5) (2024)
Arielle Elkrief, Meagan Montesion, Smruthy S Sivakumar, Caryn R Hale, Anita S Bowman, Ayyuce Begum Bektas, Martina Bradic, Wenfei Kang, Eric Chan, Pooja Gogia, Katia Manova-Todorova, Douglas A Mata, Jacklynn V Egger, Hira Rizvi, Nicolas D Socci, Daniel W Kelly, Eric Rosiek, Fanli Meng, Grittney Tam, Ning Fan, Alexander E Drilon, Helena Alexandra Yu, Gregory J Riely, Natasha Rekhtman, Álvaro Quintanal-Villalonga, Snjezana Dogan, Umeshkumar K Bhanot, Mithat Gönen, Brian R Loomis, Matthew D Hellmann, Adam J Schoenfeld, Marc Ladanyi, Charles M Rudin, Chad M Vanderbilt
Intratumoral Escherichia Is Associated With Improved Survival to Single-Agent Immune Checkpoint Inhibition in Patients With Advanced Non-Small-Cell Lung Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-Related Colitis Is Associated with Fecal Microbial Dysbiosis and Can Be Mitigated by Fecal Microbiota Transplantation. Cancer immunology research 12 (3) (2024)
Naiyer Rizvi, Foluso O Ademuyiwa, Z Alexander Cao, Helen X Chen, Robert L Ferris, Sarah B Goldberg, Matthew D Hellmann, Ranee Mehra, Ina Rhee, Jong Chul Park, Harriet M Kluger, Hussein A Tawbi, Ryan J Sullivan
Society for Immunotherapy of Cancer (SITC) consensus definitions for resistance to combinations of immune checkpoint inhibitors with chemotherapy. Journal for immunotherapy of cancer 11 (3) (2023)
Miguel Lopez de Rodas, Yvonne Wang, Gang Peng, Jian-Lei Gu, Mari A Mino-Kenudson, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin F Gainor, Hongyu Zhao, Kurt A Schalper
Objective analysis and clinical significance of the spatial tumor infiltrating lymphocyte patterns in non-small cell lung cancer (NSCLC). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation. Cancer immunology research (2023)
Noura J Choudhury, Jessica A Lavery, Samantha Brown, Ino De Bruijn, Justin Jee, Thinh Ngoc Tran, Hira A Rizvi, Kathryn C Arbour, Karissa A Whiting, Ronglai Shen, Matthew D Hellmann, Philippe L Bedard, Celeste Yu, Natasha B Leighl, Michele L LeNoue-Newton, Christine M Micheel, Jeremy L Warner, Michelle S Ginsberg, Andrew J Plodkowski, Jeffrey Girshman, Peter Sawan, Shirin Pillai, Shawn M Sweeney, Kenneth L Kehl, Katherine S Panageas, Nikolaus Schultz, Deborah Schrag, Gregory J Riely
The GENIE BPC NSCLC cohort: a real-world repository integrating standardized clinical and genomic data for 1,846 patients with non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Rohit Thummalapalli, Biagio Ricciuti, Chaitanya Bandlamudi, Daniel M Muldoon, Hira A Rizvi, Arielle Elkrief, Jia Luo, Joao M Victor Alessi, Federica Pecci, Giuseppe Lamberti, Alessandro Di Federico, Lingzhi Hong, Jianjun Zhang, John Victor Heymach, Don L Gibbons, Andrew J Plodkowski, Vignesh Ravichandran, Mark T A Donoghue, Chad M Vanderbilt, Marc Ladanyi, Charles M Rudin, Mark G Kris, Gregory J Riely, Jamie E Chaft, Matthew D Hellmann, Natalie I Vokes, Mark M Awad, Adam J Schoenfeld
Clinical and molecular features of long-term response to immune checkpoint inhibitors in patients with advanced non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation. Cancer immunology research (2023)
Arielle Elkrief, Joao M Victor Alessi, Biagio Ricciuti, Samantha Brown, Hira Rizvi, Isabel R Preeshagul, Xinan Wang, Federica Pecci, Alessandro Di Federico, Giuseppe Lamberti, Jacklynn V Egger, Jamie E Chaft, Charles M Rudin, Gregory J Riely, Mark G Kris, Marc Ladanyi, Yuan Chen, Matthew D Hellmann, Ronglai Shen, Mark M Awad, Adam J Schoenfeld
Efficacy of PD-(L)1 blockade monotherapy compared with PD-(L)1 blockade plus chemotherapy in first-line PD-L1-positive advanced lung adenocarcinomas: a cohort study. Journal for immunotherapy of cancer 11 (7) (2023)
Miguel Lopez de Rodas, Yvonne Wang, Gang Peng, Jian-Lei Gu, Mari A Mino-Kenudson, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin F Gainor, Hongyu Zhao, Kurt A Schalper
Objective analysis and clinical significance of the spatial tumor infiltrating lymphocyte patterns in non-small cell lung cancer (NSCLC). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Naiyer Rizvi, Foluso O Ademuyiwa, Z Alexander Cao, Helen X Chen, Robert L Ferris, Sarah B Goldberg, Matthew D Hellmann, Ranee Mehra, Ina Rhee, Jong Chul Park, Harriet M Kluger, Hussein A Tawbi, Ryan J Sullivan
Society for Immunotherapy of Cancer (SITC) consensus definitions for resistance to combinations of immune checkpoint inhibitors with chemotherapy. Journal for immunotherapy of cancer 11 (3) (2023)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation. Cancer immunology research (2023)
Sara E Schad, Andrew Chow, Levi Mark Mangarin, Heng Pan, Jiajia Zhang, Nicholas Ceglia, Justina X Caushi, Nicole Malandro, Roberta Zappasodi, Mathieu Gigoux, Daniel Hirschhorn, Sadna Budhu, Masataka Amisaki, Monica B Arniella, David Redmond, Jamie E Chaft, Patrick M Forde, Justin F Gainor, Matthew D Hellmann, Vinod P Balachandran, Sohrab P Shah, Kellie N Smit, Drew M Pardoll, Olivier Elemento, Jedd D Wolchok, Taha Merghoub
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions. The Journal of experimental medicine 219 (6) (2022)
Miguel Lopez de Rodas, Venkata Nagineni, Arvind Ravi, Ila J Datar, Mari A Mino-Kenudson, German Corredor, Cristian Barrera, Lindsey Behlman, David L Rimm, Roy S Herbst, Anant Madabhushi, Jonathan W Riess, Vamsidhar Velcheti, Matthew D Hellmann, Justin Gainor, Kurt A Schalper
Role of tumor infiltrating lymphocytes and spatial immune heterogeneity in sensitivity to PD-1 axis blockers in non-small cell lung cancer. Journal for immunotherapy of cancer 10 (6) (2022)
Adam J Schoenfeld, Hira A Rizvi, Danish Memon, Narek Shaverdian, Matthew J Bott, Jennifer L Sauter, C Jillian Tsai, Jayon Lihm, David Hoyos, Andrew J Plodkowski, Rocio Perez-Johnston, Peter Sawan, Jacklynn V Egger, Benjamin D Greenbaum, Andreas Rimner, Gregory J Riely, Charles M Rudin, Valerie W Rusch, Daniel R Gomez, Matthew D Hellmann
Systemic and Oligo-Acquired Resistance to PD-(L)1 Blockade in Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (17) (2022)
Ramaswamy Govindan, Charu Aggarwal, Scott J Antonia, Marianne Davies, Steven M Dubinett, Andrea Ferris, Patrick M Forde, Edward B Garon, Sarah B Goldberg, Raffit Hassan, Matthew D Hellmann, Fred R Hirsch, Melissa L Johnson, Shakun Malik, Daniel Morgensztern, Joel W Neal, Jyoti D Patel, David L Rimm, Sarah Sagorsky, Lawrence H Schwartz, Boris Sepesi, Roy S Herbst
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lung cancer and mesothelioma. Journal for immunotherapy of cancer 10 (5) (2022)
David Hoyos, Roberta Zappasodi, Isabell Schulze, Zachary Sethna, Kelvin César de Andrade, Dean F Bajorin, Chaitanya Bandlamudi, Margaret K Callahan, Samuel A Funt, Sine Reker Hadrup, Jeppe S Holm, Jonathan E Rosenberg, Sohrab P Shah, Ignacio Vàzquez-García, Jorge S Reis-Filho, Michelle Wu, Dmitriy Zamarin, Laura F Campitelli, Edward J Osborne, Mark Klinger, Harlan S Robins, Payal P Khincha, Sharon A Savage, Vinod P Balachandran, Jedd D Wolchok, Matthew D Hellmann, Taha Merghoub, Arnold J Levine, Marta Łuksza, Benjamin D Greenbaum
Fundamental immune-oncogenicity trade-offs define driver mutation fitness. Nature 606 (7912) (2022)
Kanika S Arora, Thinh Ngoc Tran, Yelena M Kemel, Miika Mehine, Ying L Liu, Subhiksha Nandakumar, Shaleigh A Smith, Angela Rose Brannon, Irina Ostrovnaya, Konrad H Stopsack, Pedram Razavi, Anton Safonov, Hira A Rizvi, Matthew D Hellmann, Joseph Vijai, Thomas C Reynolds, James A Fagin, Jian Carrot-Zhang, Kenneth Offit, David B Solit, Marc Ladanyi, Nikolaus Schultz, Ahmet Zehir, Carol L Brown, Zsofia K Stadler, Debyani Chakravarty, Chaitanya Bandlamudi, Michael F Berger
Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort. Cancer discovery 12 (11) (2022)
Semanti Mukherjee, Chaitanya Bandlamudi, Matthew D Hellmann, Yelena M Kemel, Esther Drill, Hira Rizvi, Kaitlyn Tkachuk, Aliya Khurram, Michael F Walsh, Marjorie G Zauderer, Diana Mandelker, Sabine Topka, Ahmet Zehir, Preethi Srinivasan, Myvizhi Esai Selvan, Maria Isabel Carlo, Karen A Cadoo, Alicia J Latham, Jada G Hamilton, Ying L Liu, Steven M Lipkin, Sami Belhadj, Gareth L Bond, Zeynep Hülya Gümüş, Robert J Klein, Marc Ladanyi, David B Solit, Mark E Robson, David R Jones, Mark G Kris, Joseph Vijai, Zsofia K Stadler, Christopher Ian Amos, Barry S Taylor, Michael F Berger, Charles M Rudin, Kenneth Offit
Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 31 (7) (2022)
Martin Reck, Jordi Remon, Matthew D Hellmann
First-Line Immunotherapy for Non-Small-Cell Lung Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (6) (2022)
Matthew D Hellmann, Nicoletta Bivi, Boris Calderón, Toshio Shimizu, Brant Delafontaine, Zhuqing Tina Liu, Anna M Szpurka, Victoria Copeland, F Stephen Hodi, Sylvie Rottey, Philippe Aftimos, Yongzhe Piao, Leena Gandhi, Violeta Regnier Galvao, Ching Ching Leow, Toshihiko Doi
Safety and Immunogenicity of LY3415244, a Bispecific Antibody Against TIM-3 and PD-L1, in Patients With Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (10) (2021)
Kathryn C Arbour, Hira Rizvi, Andrew J Plodkowski, Matthew D Hellmann, Andrea Knezevic, Glenn Heller, Helena A Yu, Marc Ladanyi, Mark G Kris, Maria E Arcila, Charles M Rudin, Piro Lito, Gregory J Riely
Treatment Outcomes and Clinical Characteristics of Patients with KRAS-G12C-Mutant Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (8) (2021)
Jia Luo, Victoria L Martucci, Zoe Quandt, Stefan Groha, Megan H Murray, Christine M Lovly, Hira Rizvi, Jacklynn V Egger, Andrew J Plodkowski, Mohsen Abu-Akeel, Isabell Schulze, Taha Merghoub, Eduardo Cardenas, Scott Huntsman, Min Li, Donglei Hu, Matthew A Gubens, Alexander Gusev, Melinda C Aldrich, Matthew D Hellmann, Elad Ziv
Immunotherapy-Mediated Thyroid Dysfunction: Genetic Risk and Impact on Outcomes with PD-1 Blockade in Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (18) (2021)
Mojdeh Shakiba, Paul Zumbo, Gabriel Espinosa-Carrasco, Laura Menocal, Friederike Dündar, Sandra E Carson, Emmanuel M Bruno, Francisco J Sánchez Rivera, Scott W Lowe, Steven Camara, Richard P Koche, Vincent P Reuter, Nicholas D Socci, Benjamin Whitlock, Fella Tamzalit, Morgan Huse, Matthew D Hellmann, Daniel K Wells, Nadine A Defranoux, Doron Betel, Mary Philip, Andrea Schietinger
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion. The Journal of experimental medicine 219 (2) (2021)
Masato Ogishi, Rui Yang, Caner Aytekin, David Langlais, Mathieu Bourgey, Taushif Khan, Fatima Al Ali, Mahbuba Rahman, Ottavia M Delmonte, Maya Chrabieh, Peng Zhang, Conor Gruber, Simon J Pelham, András N Spaan, Jérémie Rosain, Wei-Te Lei, Scott Drutman, Matthew D Hellmann, Margaret K Callahan, Matthew J Adamow, Phillip Wong, Jedd D Wolchok, Geetha Rao, Cindy S Ma, Yuka Nakajima, Tomonori Yaguchi, Kenji Chamoto, Samuel C Williams, Jean François Emile, Flore Rozenberg, Michael S Glickman, Franck Rapaport, Gaspard Kerner, Garrett Allington, Ilhan Tezcan, Deniz Çağdaş Ayvaz, Ferda O Hosnut, Figen Dogu, Aydan Ikinciogullari, V Koneti Rao, Leena Kainulainen, Vivien Béziat, Jacinta Bustamante, Silvia Vilarinho, Richard P Lifton, Bertrand Boisson, Laurent Abel, Dusan Bogunovic, Nico Marr, Luigi Daniele Notarangelo, Stuart G Tangye, Tasuku Honjo, Philippe Gros, Stéphanie Boisson-Dupuis, Jean Laurent Casanova
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child. Nature medicine 27 (9) (2021)
Kevin Litchfield, James L Reading, Emilia L Lim, Hang Xu, Po Liu, Maise Al-Bakir, Yien Ning Sophia Wong, Andrew Rowan, Samuel A Funt, Taha Merghoub, David Perkins, Martin Lauss, Inge Marie Svane, Göran Jönsson, Javier Herrero, James Larkin, Sergio A Quezada, Matthew D Hellmann, Samra Turajlic, Charles Swanton
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity. Nature communications 11 (1) (2020)
Jia Luo, Hira Rizvi, Jacklynn V Egger, Isabel R Preeshagul, Jedd D Wolchok, Matthew D Hellmann
Impact of PD-1 Blockade on Severity of COVID-19 in Patients with Lung Cancers. Cancer discovery 10 (8) (2020)
Adam J Schoenfeld, Chai Bandlamudi, Jessica A Lavery, Joseph Montecalvo, Azadeh Namakydoust, Hira Rizvi, Jacklynn V Egger, Carla P Concepcion, Sonal Paul, Maria E Arcila, Yahya Daneshbod, Jason Chang, Jennifer L Sauter, Amanda Beras, Marc Ladanyi, Tyler Jacks, Charles M Rudin, Barry S Taylor, Mark T A Donoghue, Glenn Heller, Matthew D Hellmann, Natasha Rekhtman, Gregory J Riely
The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (21) (2020)
Matthew D Hellmann, Pasi A Jänne, Mateusz Opyrchal, Navid Hafez, Luis E Raez, Dmitry I Gabrilovich, Fang Wang, Jane B Trepel, Min-Jung Lee, Akira Yuno, Susan Brouwer, Serap Sankoh, Lei Wang, David Tamang, Emmett V Schmidt, Michael L Meyers, Suresh S Ramalingam, Elaine Shum, Peter Ordentlich
Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (4) (2020)
Xuemei Ji, Semanti Mukherjee, Maria Teresa Landi, Yohan Bosse, Philippe Joubert, Dakai Zhu, Ivan Gorlov, Xiangjun Xiao, Younghun Han, Olga Gorlova, Rayjean J Hung, Yonathan Brhane, Robert Carreras-Torres, David Chistopher Christiani, Neil Caporaso, Mattias Johansson, Geoffrey Liu, Stig Egil Bojesen, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardón, Gadi Rennert, Chu Chen, Jinyoung Byun, Konstantin H Dragnev, John K Field, Lambertus Fa Kiemeney, Philip Lazarus, Shan Zienolddiny, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Pier A Bertazzi, Angela Cecilia Pesatori, Nancy Diao, Li Su, Lei Song, Ruyang Zhang, Natasha Leighl, Jakob Sidenius Johansen, Anders Mellemgaard, Walid Saliba, Christopher Haiman, Lynne Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardón, Erik H F M van der Heijden, Jin Hee Kim, Michael P A Davies, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, Erich Wichmann, Thomas Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances Shepherd, Ming Sound Tsao, Susanne M Arnold, Eric B Haura, Ciprian Nicolae Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeriya, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Lesley M Butler, Kenneth Offit, Preethi Srinivasan, Chaitanya Bandlamudi, Matthew D Hellmann, David B Solit, Mark E Robson, Charles M Rudin, Zsofia K Stadler, Barry S Taylor, Michael F Berger, Richard S Houlston, John McLaughlin, Victoria L Stevens, David C Nickle, Ma'en Obeidat, Hidde J Haisma, María Soler Artigas, Sanjay Shete, Hermann Brenner, Stephen J Chanock, Paul J Brennan, James D McKay, Christopher Ian Amos
Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature communications 11 (1) (2020)
Qu Zhang, Jia Luo, Song Wu, Han Si, Chen Gao, Wenjing Xu, Shaad E Abdullah, Brandon W Higgs, Phillip A Dennis, Michiel S van der Heijden, Neil H Segal, Jamie E Chaft, Todd Hembrough, J Carl Barrett, Matthew D Hellmann
Prognostic and Predictive Impact of Circulating Tumor DNA in Patients with Advanced Cancers Treated with Immune Checkpoint Blockade. Cancer discovery 10 (12) (2020)
Matthew D Hellmann, Barzin Y Nabet, Hira Rizvi, Aadel A Chaudhuri, Daniel K Wells, Mark P S Dunphy, Jacob J Chabon, Chih Long Liu, Angela B Hui, Kathryn C Arbour, Jia Luo, Isabel R Preeshagul, Everett J Moding, Diego Almanza, Rene F Bonilla, Jennifer L Sauter, Hyejin Choi, Megan Tenet, Mohsen Abu-Akeel, Andrew J Plodkowski, Rocio Perez Johnston, Christopher H Yoo, Ryan B Ko, Henning Stehr, Linda Gojenola, Heather A Wakelee, Sukhmani K Padda, Joel W Neal, Jamie E Chaft, Mark G Kris, Charles M Rudin, Taha Merghoub, Bob T Li, Ash A Alizadeh, Maximilian Diehn
Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (12) (2020)
Kathryn C Arbour, Anh Tuan Luu, Jia Luo, Hira Rizvi, Andrew J Plodkowski, Mustafa Sakhi, Kevin B Huang, Subba R Digumarthy, Michelle S Ginsberg, Jeffrey Girshman, Mark G Kris, Gregory J Riely, Adam Yala, Justin F Gainor, Regina Barzilay, Matthew D Hellmann
Deep Learning to Estimate RECIST in Patients with NSCLC Treated with PD-1 Blockade. Cancer discovery 11 (1) (2020)
Jiajia Zhang, Zhicheng Ji, Justina X Caushi, Margueritta El Asmar, Valsamo Anagnostou, Tricia R Cottrell, Hok Yee Chan, Prerna Suri, Haidan Guo, Taha Merghoub, Jamie E Chaft, Joshua E Reuss, Ada J Tam, Richard L Blosser, Mohsen Abu-Akeel, John-William Sidhom, Ni Zhao, Jinny S Ha, David R Jones, Kristen A Marrone, Jarushka Naidoo, Edward Gabrielson, Janis M Taube, Victor E Velculescu, Julie R Brahmer, Franck Housseau, Matthew D Hellmann, Patrick M Forde, Drew M Pardoll, Hongkai Ji, Kellie N Smith
Compartmental Analysis of T-cell Clonal Dynamics as a Function of Pathologic Response to Neoadjuvant PD-1 Blockade in Resectable Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (6) (2019)
Ila Datar, Miguel F Sanmamed, Jun Wang, Brian S Henick, Jungmin Choi, Ti Badri, Weilai Dong, Nikita Mani, Maria Toki, Luis D Mejías, Maria D Lozano, Jose Luis Perez-Gracia, Vamsidhar Velcheti, Matthew D Hellmann, Justin F Gainor, Kristen McEachern, David Jenkins, Konstantinos Syrigos, Katerina Politi, Scott Gettinger, David L Rimm, Roy S Herbst, Ignacio Melero, Lieping Chen, Kurt A Schalper
Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non-Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (15) (2019)
Siwen Hu-Lieskovan, Aaron Lisberg, Jesse M Zaretsky, Tristan R Grogan, Hira Rizvi, Daniel K Wells, James Carroll, Amy Cummings, John Madrigal, Benjamin Jones, Jacklin Gukasyan, I Peter Shintaku, Dennis Slamon, Steven Dubinett, Jonathan W Goldman, David Elashoff, Matthew D Hellmann, Antoni Ribas, Edward B Garon
Tumor Characteristics Associated with Benefit from Pembrolizumab in Advanced Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (16) (2019)
Lawrence Fong, Andrew Hotson, John D Powderly, Mario Sznol, Rebecca S Heist, Toni K Choueiri, Saby George, Brett G M Hughes, Matthew D Hellmann, Dale R Shepard, Brian I Rini, Shivaani Kummar, Amy M Weise, Matthew J Riese, Ben Markman, Leisha A Emens, Daruka Mahadevan, Jason John Luke, Ginna Laport, Joshua D Brody, Leonel Hernandez-Aya, Philip Bonomi, Jonathan W Goldman, Lyudmyla Berim, Daniel J Renouf, Rachel A Goodwin, Brian Munneke, Po Y Ho, Jessica Hsieh, Ian McCaffery, Long Kwei, Stephen B Willingham, Richard A Miller
Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer. Cancer discovery 10 (1) (2019)
Alexandra Snyder, Michael P Morrissey, Matthew D Hellmann
Use of Circulating Tumor DNA for Cancer Immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (23) (2019)
Matthew D Hellmann, Luis Paz-Ares, Reyes Bernabe Caro, Bogdan Zurawski, Sang-We Kim, Enric Carcereny Costa, Keunchil Park, Aurelia Alexandru, Lorena Lupinacci, Emmanuel de la Mora Jimenez, Hiroshi Sakai, Istvan Albert, Alain Vergnenegre, Solange Peters, Konstantinos Syrigos, Fabrice Barlesi, Martin Reck, Hossein Borghaei, Julie R Brahmer, Kenneth J O'Byrne, William J Geese, Prabhu Bhagavatheeswaran, Sridhar K Rabindran, Ravi S Kasinathan, Faith E Nathan, Suresh S Ramalingam
Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer. The New England journal of medicine 381 (21) (2019)
Matthew D Hellmann, Alexandra Snyder
Adding to the checkpoint blockade armamentarium. Nature medicine 25 (2) (2019)
Robert M Samstein, Chung-Han Lee, Alexander N Shoushtari, Matthew D Hellmann, Ronglai Shen, Yelena Y Janjigian, David A Barron, Ahmet Zehir, Emmet J Jordan, Antonio Omuro, Thomas J Kaley, Sviatoslav M Kendall, Robert J Motzer, A Ari Hakimi, Martin H Voss, Paul Russo, Jonathan Rosenberg, Gopakumar V Iyer, Bernard H Bochner, Dean F Bajorin, Hikmat A Al-Ahmadie, Jamie E Chaft, Charles M Rudin, Gregory J Riely, Shrujal Baxi, Alan L Ho, Richard J Wong, David G Pfister, Jedd D Wolchok, Christopher A Barker, Philip H Gutin, Cameron W Brennan, Viviane Tabar, Ingo K Mellinghoff, Lisa M DeAngelis, Charlotte E Ariyan, Nancy Lee, William D Tap, Mrinal M Gounder, Sandra P D'Angelo, Leonard Saltz, Zsofia K Stadler, Howard I Scher, Jose Baselga, Pedram Razavi, Christopher A Klebanoff, Rona Yaeger, Neil H Segal, Geoffrey Y Ku, Ronald P DeMatteo, Marc Ladanyi, Naiyer A Rizvi, Michael F Berger, Nadeem Riaz, David B Solit, Timothy A Chan, Luc G T Morris
Tumor mutational load predicts survival after immunotherapy across multiple cancer types. Nature genetics 51 (2) (2019)
Kyung Hae Jung, Patricia LoRusso, Howard Burris, Michael Gordon, Yung-Jue Bang, Matthew D Hellmann, Andres Cervantes, Maria Ochoa de Olza, Aurelien Marabelle, F Stephen Hodi, Myung-Ju Ahn, Leisha A Emens, Fabrice Barlesi, Omid Hamid, Emiliano Calvo, David McDermott, Hatem Soliman, Ina Rhee, Ray Lin, Tony Pourmohamad, Julia Suchomel, Amy Tsuhako, Kari Morrissey, Sami Mahrus, Roland Morley, Andrea Pirzkall, S Lindsey Davis
Phase I Study of the Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Navoximod (GDC-0919) Administered with PD-L1 Inhibitor (Atezolizumab) in Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (11) (2019)
Diana Miao, Claire A Margolis, Wenhua Gao, Martin H Voss, Wei Li, Dylan J Martini, Craig Norton, Dominick Bosse, Stephanie M Wankowicz, Dana Cullen, Christine Horak, Megan Wind-Rotolo, Adam Tracy, Marios Giannakis, Frank Stephen Hodi, Charles G Drake, Mark W. Ball, Mohamad E Allaf, Alexandra Snyder, Matthew D Hellmann, Thai H Ho, Robert J Motzer, Sabina Signoretti, William G Kaelin, Toni K Choueiri, Eliezer Van Allen
Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma. Science (New York, N.Y.) 359 (6377) (2018)
Matthew D Hellmann, Tudor-Eliade Ciuleanu, Adam Pluzanski, Jong Seok Lee, Gregory A Otterson, Clarisse Audigier-Valette, Elisa Minenza, Helena Linardou, Sjaak Burgers, Pamela Salman, Hossein Borghaei, Suresh S Ramalingam, Julie Brahmer, Martin Reck, Kenneth J O'Byrne, William J Geese, George Green, Han Chang, Joseph Szustakowski, Prabhu Bhagavatheeswaran, Diane Healey, Yali Fu, Faith Nathan, Luis Paz-Ares
Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden. The New England journal of medicine 378 (22) (2018)
Valsamo Anagnostou, Patrick M Forde, James R White, Noushin Niknafs, Carolyn Hruban, Jarushka Naidoo, Kristen Marrone, I K Ashok Sivakumar, Daniel C Bruhm, Samuel Rosner, Jillian Phallen, Alessandro Leal, Vilmos Adleff, Kellie N Smith, Tricia R Cottrell, Lamia Rhymee, Doreen N Palsgrove, Christine L Hann, Benjamin Levy, Josephine Feliciano, Christos Georgiades, Franco Verde, Peter B Illei, Qing Kay Li, Edward Gabrielson, Malcolm V Brock, James M Isbell, Jennifer L Sauter, Janis Taube, Robert B Scharpf, Rachel Karchin, Drew M Pardoll, Jamie E Chaft, Matthew D Hellmann, Julie R Brahmer, Victor E Velculescu
Dynamics of Tumor and Immune Responses during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer. Cancer research 79 (6) (2018)
Patrick M Forde, Jamie E Chaft, Kellie N Smith, Valsamo Anagnostou, Tricia R Cottrell, Matthew D Hellmann, Marianna Zahurak, Stephen C Yang, David R Jones, Stephen Broderick, Richard J Battafarano, Moises J Velez, Natasha Rekhtman, Zachary Olah, Jarushka Naidoo, Kristen A Marrone, Franco Verde, Haidan Guo, Jiajia Zhang, Justina X Caushi, Hok Yee Chan, John-William Sidhom, Robert B Scharpf, James White, Edward Gabrielson, Hao Wang, Gary L Rosner, Valerie Rusch, Jedd D Wolchok, Taha Merghoub, Janis M Taube, Victor E Velculescu, Suzanne L Topalian, Julie R Brahmer, Drew M Pardoll
Neoadjuvant PD-1 Blockade in Resectable Lung Cancer. The New England journal of medicine 378 (21) (2018)
Bertrand Routy, Emmanuelle Le Chatelier, Lisa Derosa, Connie P M Duong, Maryam Tidjani Alou, Romain Daillère, Aurélie Fluckiger, Meriem Messaoudene, Conrad Rauber, Maria P Roberti, Marine Fidelle, Caroline Flament, Vichnou Poirier-Colame, Paule Opolon, Christophe Klein, Kristina Iribarren, Laura Mondragón, Jacquelot N, Bo Qu, Gladys Ferrere, Céline Clémenson, Laura Mezquita, Jordi Remon Masip, Charles Naltet, Solenn Brosseau, Coureche Kaderbhai, Corentin Richard, Hira Rizvi, Florence Levenez, Nathalie Galleron, Benoit Quinquis, Nicolas Pons, Bernhard Ryffel, Véronique Minard-Colin, Patrick Gonin, Jean-Charles Soria, Eric Deutsch, Yohann Loriot, François Ghiringhelli, Gérard Zalcman, François Goldwasser, Bernard Escudier, Matthew D Hellmann, Alexander Eggermont, Didier Raoult, Laurence Albiges, Guido Kroemer, Laurence Zitvogel
Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Science (New York, N.Y.) 359 (6371) (2017)
Alexandra Snyder, Tavi Nathanson, Samuel A Funt, Arun Ahuja, Jacqueline Buros, Matthew D Hellmann, Eliza Chang, Bülent Arman Aksoy, Hikmat Al-Ahmadie, Erik Yusko, Marissa Vignali, Sharon Benzeno, Mariel Boyd, Meredith Moran, Gopa Iyer, Harlan S Robins, Elaine R Mardis, Taha Merghoub, Jeff Hammerbacher, Jonathan E Rosenberg, Dean F Bajorin
Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis. PLoS medicine 14 (5) (2017)